A rupture disc is the most aseptic method to secure in case of overpressure. The process is guaranteed to be 100% closed by a rupture disc. This is in contrast with a safety valve (spring loaded) which can open and close unnoticed and thus can cause infection. The pressure range of the rupture disc is always exactly the same, the bursting pressure does not expire. So it does not need to be tested, as such is the case with a safety valve (spring loaded). Not only a production stop is avoided it also gives time and cost savings in maintenance.
It may be of value to place a spring loaded safety valve after a rupture disc. The system will be closed after a ruptured disc. A detection of the bursting process gives the supervisor a signal about the overpressure that is generated. This makes a rupture disc the most ideal setup for a sterile process.
Bi-directional, Ultralow Burst Pressure
Burst Check Line
Smooth, Reverse-acting, Lowest Burst Pressure